I forgot to mention Marble Madness, Faery Tale Adventure, Gee Bee Air Rally and the granddaddy of all Amiga games, Mindwalker. They were (at the time) unique and innovative and served as forerunners to future game genres.
I agree with the inclusion of Wings, but I would for sure have more CinemaWare titles in my Top 50...especially Rocket Ranger, It Came From the Desert and Defender of the Crown.
The Monkey Island games and Sensi World of Soccer would be in my top 50....Having said that Rome AD92 holds a special place, just way too many to chose from!
I have fond memories of my Amiga 500 and 1200. Games I played to death were Sensible Soccer, Chaos Engine, Speedball 2 and Blood Money. I adore this range of machines.